Online first

Acta Reumatológica Portuguesa - Online First: 2018-10-14

Systemic sclerosis and myositis as a paraneoplastic syndrome secondary to multiple myeloma

Santos-Faria D, Silva JL, Sousa-Neves J, Rodrigues JR, Afonso C, Peixoto D


We present a case of paraneoplastic systemic sclerosis (SSc) and myositis associated to a multiple myeloma (MM) in a 52-year-old Caucasian man. After MM treatment, skin and muscle changes improved, with no further relapses. Although rare, “scleroderma-like” or myositis lesions may be associated with MM. However, to the best of our knowledge, this is the first case reporting these two clinical conditions simultaneously associated with MM.