ARP Rheumatology
ARP Rheumatology
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Article

ARP Rheumatology
Original article

Prevalence and clinical manifestations of Erasmus syndrome in systemic sclerosis: a cross-sectional study

Authors

Azevedo S, Sousa-Neves J, Santos-Faria D, Silva JL, Rodrigues JR, Peixoto D, Tavares-Costa J, Alcino S, Afonso C, Teixeira F

Abstract

Introduction: Erasmus syndrome (ErS) is a rare entity in which Systemic Sclerosis (SSc) develops following exposure to silica, with or without associated silicosis. The objectives of this study were: 1) to evaluate the prevalence of ErS in our SSc cohort; 2) to characterize the cases; 3) to evaluate the clinical and laboratory characteristics of SSc in patients with (Ers) or without silica exposure. Methods: Cross-sectional and analytical study. Sociodemographic, clinical and laboratory data were collected from all patients with SSc diagnosed in our department according to ACR / EULAR criteria. Data on professional activity and possible exposure to silica were obtained by phone interview. Results: Among 48 patients with SSc, the prevalence of ErS was 16.7% (8/48). All cases identified were male, corresponding to 72.7% of men with SSc followed at our department. There was a statistically significant association between ErS and male gender (p

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Publication:

2020-08-15

Pubmed:

Cite:

Soraia Azevedo, Joana Sousa-Neves, Daniela Santos-Faria, Joana Leite Silva, Joana Ramos Rodrigues, Daniela Peixoto, José Tavares-Costa, Sérgio Alcino, Carmo Afonso, Filipa Teixeira. Prevalence and clinical manifestations of Erasmus syndrome in systemic sclerosis: a cross-sectional study. ARP, Vol 45, nº3 2020:183-190. PMID: 33139685
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